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目的:研究高尿酸血症与颈动脉内中膜厚度之间的关系。方法:选取2012年12月-2015年12月于本院正常体检者中高尿酸血症患者137例设为观察组,血尿酸水平正常者129例设为对照组。观察组和对照组均采用彩色多普勒超声检查测量其颈动脉内中膜厚度。结果:与血尿酸水平正常人群相比,高尿酸血症人群颈动脉内中膜厚度显著增大,差异具有统计学意义(P<0.05)。结论:血浆尿酸水平升高,颈动脉内中膜厚度也相应增大,血浆尿酸水平的高低可以在一定程度上间接反映颈动脉内中膜硬化的程度。
Objective: To study the relationship between hyperuricemia and carotid intima-media thickness. Methods: 137 patients with hyperuricemia in our hospital from December 2012 to December 2015 were selected as observation group and 129 patients with normal serum uric acid level as control group. The observation group and the control group were measured by color Doppler ultrasound carotid intima-media thickness. Results: The carotid intima-media thickness of hyperuricemia group was significantly higher than that of normal uric acid level group (P <0.05). Conclusion: The level of plasma uric acid increases and the thickness of carotid intima-media increases accordingly. The level of plasma uric acid may reflect indirectly the extent of carotid intima-media thickness to a certain extent.