目的:提高不典型脊柱结核诊断水平。方法:回顾分析最初被误诊为其他疾病的16例不典型脊柱结核患者的临床资料。结果:本组16例患者均经影像及病理活检确诊为脊柱结核,经给予正规抗痨治疗后行病灶清除术,均获痊愈。结论:不典型脊柱结核容易误诊,应提高认识,并结合影像及病理活检等检查及时诊治,减少误诊。 Objective: To improve the diagnosis of atypical spinal tuberculosis. Methods: The clinical data of 16 patients with atypical spinal tuberculosis initially misdiagnosed as other diseases were retrospectively analyzed. Results: All the 16 patients in this group were diagnosed as spinal tuberculosis by imaging and pathological biopsy. All patients were cured after giving normal anti-tuberculosis treatment. Conclusion: Atypical spinal tuberculosis is easy to be misdiagnosed. Awareness should be raised. Combined with imaging and pathological biopsy, timely diagnosis and treatment should be done to reduce misdiagnosis.