用AB(pH2.5)/PAS、HID及CEA(ABC法)对48例胃粘液细胞癌及其淋巴结进行染色观察,对照HE染色,结果表明应用上述方法染色可提高淋巴结转移检出率33.1%,其中AB(pH2.5)/PAS法显示了很强的特异性和敏感性,较HID和CEA法优越。淋巴结微小转移灶多为PAS阳性细胞,说明幼稚的癌细胞分泌中性粘液、侵袭力强、容易转移并先发生转移。CEA标记结果显示本肿瘤有分化越差、越幼稚其CEA含量越少的现象。 48 cases of gastric mucinous carcinoma and its lymph nodes were stained with AB (pH2.5)/PAS, HID and CEA (ABC method), and HE staining was performed. The results showed that the above method can improve the detection rate of lymph node metastasis by 33.1%. Among them, the AB(pH2.5)/PAS method showed a strong specificity and sensitivity, which is superior to the HID and CEA methods. Small lymph node metastases are mostly PAS positive cells, indicating that naive cancer cells secrete neutral mucus, strong invasiveness, easy metastasis and metastasis. CEA marker results showed that the tumor had poorer differentiation and the younger the CEA content was less.