论文部分内容阅读
目的研究VEGF-C、Survivin在淋巴管瘤组织中表达的相互关系。方法应用免疫组化S-P方法检测62例淋巴管瘤标本,20例胸导管标本VEGF-C、Survivin的表达情况。结果在淋巴管瘤组织中Survivin表达阳性率为22.58%%(14/62);VEGF-C阳性率为27.41%(17/62),两者阳性率差异无统计学意义(P>0.05)。结论 VEGF-C、Survivin在淋巴管瘤与正常淋巴管组织中阳性表达差异无统计学意义,淋巴管瘤属于正常脉管内皮细胞增长范畴;但同一病理组织中两者阳性表达存在着正相关,VEGF-C、Survivin可能与淋巴管瘤内皮细胞增殖相关。
Objective To study the expression of VEGF-C and Survivin in lymphangioma tissues. Methods Immunohistochemical S-P method was used to detect the expression of VEGF-C and Survivin in 62 specimens of lymphangioma and 20 specimens of thoracic duct. Results The positive rate of Survivin expression in lymphangioma was 22.58% (14/62). The positive rate of VEGF-C was 27.41% (17/62). There was no significant difference in the positive rate of Survivin between the two groups (P> 0.05). Conclusions The positive expressions of VEGF-C and Survivin in lymphangioma and normal lymphatic tissue have no statistical significance. Lymphangioma belongs to the normal vascular endothelial cell growth category. However, there is a positive correlation between the expression of VEGF-C and Survivin in the same pathological tissue, VEGF-C, Survivin may be related to the proliferation of lymphangioma endothelial cells.