报告1例皮肤根霉病。患者男,50岁。因丙型肝炎、肝硬化接受原位肝移植术。术后第12天,右上肢前臂出现红斑、肿胀并渐扩大,皮肤呈黑色坏疽样外观。右上肢、肩部、腋下、胸背疼痛。皮损组织病理检查示血管周围有粗大、无分隔直角菌丝,血管内真菌栓塞。真菌学检查证实为接合菌病根霉属。后经聚合酶链反应(PCR)鉴定为小孢根霉。对上肢感染组织行清创术、截肢,并予以两性霉素B脂质体治疗3周。经治疗肿胀减轻,疼痛消失,目前仍在治疗中。 Report 1 case of skin Rhizopus. Male patient, 50 years old. Due to hepatitis C, liver cirrhosis underwent orthotopic liver transplantation. On the 12th day after operation, the erythema of the upper right forearm appeared, swelling and gradually enlarged, and the appearance of black gangrenous skin. Right upper limb, shoulder, armpit, chest and back pain. Histopathological examination of the lesion revealed a thick, non-segmented, myocular mycelium around the blood vessels and embolization of the intravascular fungus. Mycological tests confirmed that the genus Rhizopus. After the polymerase chain reaction (PCR) identified as Rhizopus sp. Debridement and amputation were performed on upper extremity infected tissues and treated with amphotericin B liposomes for 3 weeks. After the treatment of swelling reduced, the pain disappeared, is still under treatment.