B—7601是我国合成的抗胆碱药,化学结构为二苯羟乙酸4—(3,5)桥丙基N—甲基哌啶酯。 经实验研究,此药的抗胆碱作用强度与东莨菪碱无显著差异,但具有较强的中枢抑制作用和抗惊厥作用,而散瞳作用则较东莨菪碱弱。因此进行动物实验,对B—7601的中枢作用与东莨菪碱作一比较,并试图以此药来加深“中药麻醉”或用它来代替东莨菪碱。 方法与结果 B-7601 is a synthetic anticholinergic drug in China with a chemical structure of 4- (3,5) n-propyl N-methylpiperidinyl diphenyloxetan. The experimental study, the drug anticholinergic intensity and scopolamine no significant difference, but has a strong central inhibitory effect and anticonvulsant effect, while the mydriatic effect is weaker than scopolamine. Therefore, animal experiments were conducted to compare the central effect of B-7601 with scopolamine and to try to use this medicine to deepen the “traditional Chinese medicine anesthesia” or use it instead of scopolamine. Methods and results