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酮体(乙酰乙酸,β-羟丁酸)在进食一般膳食的人和大鼠体内的血中浓度约为0.1mM,可随生理变化有所增加;在各种应激情况下其浓度范围变化很大.由于酮体可代替葡萄糖为许多组织器官提供能量,抑制肌肉蛋白质分解,减少肌肉氨基酸的释放.起到节约蛋白质的作用,故它在应激情况下的代谢变化已引起人们的注意.一、酮体的产生、利用与自身调节酮体的生成率有赖于肝脏摄取血中游离脂肪酸(FFA)的量,而血酮体浓度则依肝
Ketone bodies (acetoacetate, beta-hydroxybutyrate) have a blood concentration of about 0.1 mM in humans and rats fed on a regular diet and may increase with physiological changes; their concentration ranges vary under various stress conditions Because ketone bodies can replace glucose for many tissues and organs to provide energy, inhibit muscle protein breakdown, reduce the release of muscle amino acids play a role in saving protein, so its metabolic changes under stress conditions has attracted people’s attention. First, the generation of ketone bodies, the use and regulation of ketone body formation rate depends on the amount of free fatty acids (FFA) in the liver uptake of blood ketone body concentration according to the liver