对126例拔除下颌阻生智齿患者随机分别采取于拔牙窝内放入甲硝唑粉、碘仿、浸庆大霉素纱布及不放药的处理方法,结果表明甲硝唑和碘仿能有效地预防干槽症的发生。对4例发生于槽症者取干槽底部组织作细菌学检查,结果表明干槽症与厌氧菌感染有密切关系。并讨论了干槽症的发病机理及甲硝唑和碘仿预防干槽症的作用机理。 126 cases of patients with mandibular impacted wisdom teeth were randomly divided into two groups: metronidazole powder, iodoform, gentamicin gauze, and no drug release. The results showed that metronidazole and iodoform were effective To prevent the occurrence of dry mouth disease. Bacteriological examination was performed on the bottom of the dry tissue of 4 patients who suffered from sufferer. The results showed that there was a close relationship between dry socket disease and anaerobic infection. The pathogenesis of dry socket disease and the mechanism of action of metronidazole and iodoform to prevent dry socket disease were also discussed.