【摘 要】
:
AIM: To determine the relationship between biliary stricture and pigment gallstone formation, and the prevention of pigment gallstones with medicine.METHODS: On
【机 构】
:
Department of Surgery, Third Hospital of Peking University,Beijing 100083, China
论文部分内容阅读
AIM: To determine the relationship between biliary stricture and pigment gallstone formation, and the prevention of pigment gallstones with medicine.METHODS: One hundred and eighteen male guinea pigs were randomly divided into four groups: stricture group (S, n = 30) underwent partial ligation of common bile duct, and fed on regular chow; S plus medicine group (S+M, n = 27) underwent the same operation but fed on medicinal chow (0.3 g chenodeoxycholic acid, 0.5 g glucurolactone, and 0.5 g aspirin were mixed up in 1.2 kg regular chow); medicinal control group (C+M, n = 30) was free of operation, and fed on medicinal chow; and control group (C, n = 31) was free of operation and fed on regular chow. One week later, laparotomy was performed, and the bile of gallbladder was collected, measured, and cultured.RESULTS: Gallstones were identified. Pigment gallstones were induced by biliary stricture in 95% (22/23) of S group. In the S+M group, the incidence of gallstone was reduced to 55% (11/20, vs S group, P<0.01). The changes of indirect bilirubin and ionized calcium in the bile were consistent with gallstone incidences.CONCLUSION: Biliary stricture can cause pigment gallstone formation in guinea pigs, and the medicines used can lower the incidence of gallstones. The bilirubin and ionized calcium play important roles in pigment gallstone formation.
其他文献
目的:研究舒适护理对创伤骨折患者术后疼痛的影响效果.方法:选取2016年2月~2018年1月期间我院收治的100例创伤骨折术后患者,采用抽签法,将其分为实验组和参照组,每组50例;参照
AIM: To study whether N-acetyltransferase 2 (NAT2) genotypes and phenotypes are associated with increased risk factor for gastric cancer in Omani patients and t
Objective:To evaluate the success rate of tuberculosis intervention programme at a specialist hospital in(?)badan,Nigeria through a retrospective study as well
目的探讨输尿管软镜联合钬激光治疗上尿路≥ 2.0 cm结石的临床疗效和安全性。方法将100例上尿路≥ 2.0 cm结石患者按照随机数字法分为对照组和观察组,每组50例。对照组采用经皮肾镜联合钬激光治疗,观察组采用输尿管软镜联合钬激光治疗。比较两组手术相关指标、结石清除率和术后总并发症发生率。结果观察组手术时间、需择期再行清石术率和住院时间明显低于对照组[(45.76 ± 9.24)min比(52.
流传度:80000000+ 如今的中国,近视发病率很高。世界卫生组织最新研究报告称,目前中国近视患者人数多达6亿,几乎是中国总人口数量的一半。这也就意味着,你身边一定有很多近视的亲朋好友。面对肥得流油的市场,不法商家纷纷打起了“视力康复”的歪主意,并声称能够“治愈近视散光”智能降低度数”,甚至“轻松摘镜”。 有吹嘘高科技神奇仪器的、有推销 “不打针、不吃药、无痛苦”,轻松恢复视力疗法的、还有许
目的 探究人文关怀护理对乳腺癌围手术期病人自我护理能力的影响.方法 随机选取我院92例乳腺癌手术患者作为观察对象,依据入院先后顺序将患者分为观察组和对照组各46例,两组
目的:评价护理干预在预防脑卒中患者胃管滑脱中的运用价值.方法:随机选取我院2013年1月-2018年1月期间住院患者中选择脑卒中患者120例作为研究对象,按照患者就诊时间将其分为
目的探讨术前超声(US)、磁共振成像(MRI)评估甲状腺乳头状癌(PTC)甲状腺外侵犯(ETE)的价值。方法回顾性分析2013年1月至2016年6月术前行US和MRI检查且病理最终确诊为PTC的90例患者,比较二者评估PTC的微小ETE、广泛ETE、ETE(微小ETE+广泛ETE)的敏感度、特异度、阳性预测值(PPV)、阴性预测值(NPV)和准确度。结果评估PTC的微小ETE,US的敏感度高于MR
目的利用玻璃体腔注射β淀粉样蛋白(amyloid β,Aβ)制作视网膜炎症模型。方法实验研究。分别向25只C57BL/6J小鼠的玻璃体腔注射2 μl PBS或不同浓度(0.5、1.0、1.5、2.0 μg/μl)的Aβ1-40 2 μl,24 h后检测视网膜神经层(简称为神经视网膜)中白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)和NLRP3炎性小体的mRNA水平变化确定适宜的Aβ诱导浓度