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目的:探讨雾化吸入布地奈德联合沙丁胺醇治疗小儿毛细支气管炎的疗效。方法:将收治的56例毛细支气管炎患儿随机分为两组,对照组26例采用抗感染、化痰、吸氧、镇静,补充液体摄入量、纠正酸中毒等常规综合治疗;治疗组30例在对照组治疗的基础上加用雾化吸入布地奈德联合沙丁胺醇治疗,观察比较两组疗效。结果:观察组治愈率76.7%,明显高于对照组的42.3%,差异有统计学意义(P<0.01),且观察组喘憋缓解时间、哮喘音消失时间、湿罗音吸收时间、咳嗽消失时间、住院时间均明显短于对照组(P<0.01),两组患儿均无明显不良反应发生。结论:对小儿毛细支气管炎在综合治疗的基础上加用雾化吸入布地奈德联合沙丁胺醇治疗可明显提高临床疗效,值得推广应用。
Objective: To investigate the efficacy of inhalation of budesonide combined with salbutamol in children with bronchiolitis. Methods: Fifty-six children with bronchiolitis were randomly divided into two groups. In the control group, 26 cases were treated with conventional therapy such as anti-infection, phlegm, oxygen inhalation, sedation, fluid supplement and acidosis correction. The treatment group Thirty patients were treated with inhaled budesonide combined with salbutamol on the basis of the control group, and the curative effect was observed and compared between the two groups. Results: The cure rate of the observation group was 76.7%, which was significantly higher than that of the control group (42.3%) (P <0.01), and the relief time of asthma, the disappearance time of asthma, the absorption time of wet rales and the disappearance of cough Time and hospital stay were significantly shorter than the control group (P <0.01), no significant adverse reactions occurred in both groups. Conclusion: Pediatric bronchiolitis combined with nebulized budesonide and salbutamol can improve the clinical curative effect on the basis of comprehensive treatment, which is worth popularizing and applying.