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目的观察黄体酮治疗先兆流产合并绒毛膜下血肿(SCH)患者的临床效果。方法选取医院收治的先兆流产合并SCH孕妇65例,按照随机单盲法分为对照组32例和观察组33例。对照组采用维生素E治疗,观察组采用黄体酮治疗。观察2组血肿吸收和腹痛消失时间;足月分娩、流产、死胎和早产等妊娠结局;胎盘植入、畸形、胎盘粘连、产后出血等并发症例数;评估保胎成功率并比较。结果观察组保胎成功率为93.94%,高于对照组的81.25%(P<0.05);观察组血肿吸收时间、腹痛消失时间均短于对照组(P<0.05);观察组足月分娩率高于对照组,流产率低于对照组(P均<0.05);观察组并发症发生率为9.09%,低于对照组的25.00%(P<0.05)。结论黄体酮对先兆流产合并SCH患者治疗效果好,可显著改善患者妊娠结局,提高保胎成功率、足月分娩率,减少流产,值得推广。
Objective To observe the clinical effect of progesterone in the treatment of patients with threatened abortion and sub-choroidal hematoma (SCH). Methods 65 cases of threatened abortion with SCH in our hospital were divided into control group (32 cases) and observation group (33 cases) according to random single-blind method. The control group was treated with vitamin E, and the observation group was treated with progesterone. The duration of abortion, abortion, stillbirth and preterm birth were observed. The incidences of placenta accreta, malformations, placenta accreta and postpartum hemorrhage were observed. The success rate of miscarriage was evaluated and compared. Results The success rate of miscarriage in observation group was 93.94%, which was higher than that in control group (81.25%, P <0.05). The time of hematoma absorption and the disappearance of abdominal pain in observation group were shorter than those in control group (P <0.05) The rate of miscarriage was lower in the control group than in the control group (P <0.05). The complication rate in the observation group was 9.09%, which was lower than that in the control group (25.00%, P <0.05). Conclusions Progesterone has a good effect on patients with threatened abortion and SCH, and can significantly improve the pregnancy outcome, improve the success rate of childbirth, full-term delivery rate and reduce abortion, which is worth promoting.