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某些细胞经致炎因子作用后表达环氧化酶－２（Ｃｏｘ－２），其基因与蛋白结构以及生化特征和Ｃｏｘ－１不完全相同。Ｃｏｘ－２可能与促炎反应有关，选择性抑制Ｃｏｘ－２的非甾体抗炎药物，其副作用较小。
Some cells express cyclooxygenase-2 (Cox-2) after being induced by inflammatory cytokines, whose genes are not exactly the same as the protein structure and biochemical characteristics and Cox-1. Cox-2 may be involved in the pro-inflammatory response, selective inhibition of Cox-2 non-steroidal anti-inflammatory drugs, the side effects of smaller.