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自1928年 Brown 撰著“异位激素的产生”以来,在近年报告中它几乎已涉及到各种已知肽与蛋白激素。肿瘤对各系统所引起的每一种效应,差不多都能用肿瘤产生的激素产物来解释(Azzpardi 1966)。由于免疫学的进展,又推动了肿瘤产物的研究。Go1d 等(1965)首先命名为肿瘤胚胎抗原。肿瘤产物有的与组织来源相对应,而另一些则不相对应、故称为异位激素,这些产物的生物学标记对鉴别肿瘤具
Since Brown’s “The production of ectopic hormones” by Brown in 1928, in recent reports it has involved almost all known peptides and protein hormones. Each of the effects of tumors on the various systems can be explained by the tumor-derived hormone product (Azzpardi 1966). Due to the progress of immunology, research on tumor products has been promoted. Go1d et al. (1965) was first named tumor embryonic antigen. Some of the tumor products correspond to the tissue source, while others are not corresponding and are called heterotopic hormones. The biological markers of these products are used to identify tumors.