目的探讨胎儿宫内生长受限早期病因诊断及治疗。方法选取2012年10月至2013年3月间在某院分娩诊断为胎儿生长受限289例病人为观察组,随机抽取同期在院分娩的298例为对照组,对两组孕妇妊娠期合并症、并发症等妊娠经过及诊断治疗情况、分娩方式、妊娠结局等相关因素进行分析。结果胎儿生长受限的发病与子痫前期(占21.5%)、羊水过少(占25.6%)、生殖道结构异常(占9%)、血液高凝状态(占50.2%)及宫内感染(占5.9%)有明确相关性;发病孕周越早,治疗效果及预后越差(P=0.001),差异有统计学意义。孕期经过治疗的FGR病例与未经治疗相比,不良结局有所改善,新生儿入NICU治疗的比率也有所减少(P=0.018),具有统计学意义。脐血氧分压对预测胎儿宫内慢性缺氧具有一定意义。结论胎儿生长受限的发病因素与子痫前期、羊水过少、生殖道结构异常、血液高凝状态和宫内感染有明确的相关性,对于胎儿生长受限应该尽早诊断,尽早治疗,同时加强宫内监测,适时终止妊娠,改善不良妊娠结局。 Objective To investigate the early etiological diagnosis and treatment of fetal growth restriction. Methods A total of 289 cases with fetal growth restriction diagnosed in a hospital from October 2012 to March 2013 were selected as the observation group. 298 cases were randomly selected as the control group during the same period of hospital delivery. Pregnancy complications in both groups , Complications such as pregnancy after diagnosis and treatment, mode of delivery, pregnancy outcomes and other related factors were analyzed. Results Fetal growth restriction was associated with preeclampsia (21.5%), oligohydramnios (25.6%), genital tract abnormalities (9%), hypercoagulable state (50.2%) and intrauterine infection Accounting for 5.9%) have a clear correlation; the earlier the gestational age, the worse the treatment effect and prognosis (P = 0.001), the difference was statistically significant. Adverse outcomes were improved in the FGR treated during pregnancy compared with no treatment, and neonatal NICU treatment was also reduced (P = 0.018), with statistical significance. Umbilical blood oxygen partial pressure prediction of fetal intrauterine chronic hypoxia has some significance. Conclusion Fetal growth restriction factors and preeclampsia, oligohydramnios, genital tract abnormalities, blood hypercoagulability state and intrauterine infection have a clear correlation, fetal growth restriction should be diagnosed as soon as possible, as soon as possible treatment, while strengthening Intrauterine monitoring, timely termination of pregnancy, improve adverse pregnancy outcomes.