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目的对胸腔内注射不同药物与肺癌胸腔积液疗效进行分析和研究。方法选取2015年8月~2016年8月在我院治疗肺癌胸腔积液的患者120例,根据用药的不同分为ABCD四个组,每组30例。A组患者给予顺铂注射治疗;B组患者给予金葡素注射治疗;C组患者给予IL-2注射治疗;D组患者给予顺铂联合金葡素注射治疗。经过四组患者的治疗后对比分析各自的治疗效果。结果 B组患者临床总有效率为96.6%,明显好于A组80.0%、C组83.3%,数据差异有显著性(P<0.05);D组患者临床总有效率为96.6%,明显好于A组、C组;D组不良反应率33.3%、B组36.6%明显低于A组63.3%和C组66.6%,数据差异有显著性(P<0.05)。结论经研究发现,采取顺铂联合金葡素注射治疗肺癌胸腔积液在临床中有着很好的治疗效果,安全性较高,不良反应少,值得推广和使用。
Objective To analyze and study the efficacy of intrathoracic injection of different drugs and pleural effusion of lung cancer. Methods A total of 120 patients with pleural effusion of lung cancer from August 2015 to August 2016 in our hospital were selected and divided into four groups of ABCD, 30 cases in each group. Patients in group A were treated with cisplatin injection; patients in group B were treated with injection of glucone; patients in group C were treated with IL-2 injection; patients in group D were treated with cisplatin and kainate injection. After the treatment of four groups of patients after comparative analysis of the respective treatment. Results The total effective rate in group B was 96.6%, which was significantly better than that in group A 80.0% and group C 83.3% (P <0.05). The total effective rate in group D was 96.6% The adverse reaction rate of group D was 33.3%, while that of group B was significantly lower than that of group A (63.3% vs 63.6%, C = 66.6%, P <0.05). Conclusion The study found that the combination of cisplatin and konjac injection for the treatment of lung cancer pleural effusion in the clinical have a very good therapeutic effect, high safety, fewer adverse reactions, it is worth promoting and use.