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为探讨慢性肾功能衰竭患者（ＣＲＦ）的载脂蛋白（Ａｐｏ）水平与血肌酐（Ｃｒ）和肌酐清除率（Ｃｃｒ）的关系。采用免疫法测定３６例ＣＲＦ病人及正常对照者２０例血清Ａｐｏ的水平。结果显示：ＣＲＦ病人血浆Ａｐｏ水平明显异常并与血肌酐及肌酐清除率相关（Ｐ＜００５）。结论说明：Ａｐｏ异常不仅是肾功能减退的结果，而且还影响肾脏疾病的进程。
To investigate the relationship between serum apomorphine (Cr) and creatinine clearance (Ccr) in patients with chronic renal failure (CRF). Immunoassay was used to determine the level of serum Apo in 20 patients with CRF and normal controls. The results showed that plasma Apo levels were significantly abnormal in patients with CRF and correlated with serum creatinine and creatinine clearance rate (P <005). Conclusion: Apo abnormalities are not only the result of renal dysfunction, but also affect the progression of kidney disease.