目的通过对260对流产夫妇进行染色体核型分析,探讨染色体异常与流产之间的关系。方法采用外周血淋巴细胞培养,常规G显带技术行染色体核型分析。结果 260对流产夫妇中,检出异常核型49例(包括染色体多态变异),异常率为9.42%。结论染色体异常是导致流产的重要原因之一,对流产夫妇进行染色体检查及遗传咨询具有重要意义。 Objective To investigate the relationship between chromosomal abnormalities and abortion by analyzing karyotypes of 260 abortion couples. Methods Chromosome karyotype analysis was performed by peripheral blood lymphocyte culture and conventional G - banding technique. Results Of 260 couples with abortion, abnormal karyotypes were detected in 49 cases (including polymorphic variation) with an abnormal rate of 9.42%. Conclusion Chromosomal abnormalities are one of the important causes of miscarriage. It is of great significance to carry out chromosome examination and genetic counseling for aborted couples.