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目的:观察头痛宁胶囊治疗偏头痛的临床疗效及安全性。方法:选择偏头痛86例,随机分成观察组46例和对照组40例。观察组采用头痛宁胶囊治疗,每次3粒,每天3次;对照组采用阿米替林25mg、每天3次,麦角胺1mg、每天3次治疗。两组均治疗4周,比较临床疗效及不良反应发生情况。结果:观察组总有效40例(87.0%),对照组为27例(67.5%);两组比较,差异显著(P<0.05)。两组均未发现严重不良反应。结论:头痛宁胶囊治疗偏头痛临床疗效优于阿米替林及麦角胺,且安全。
Objective: To observe the clinical curative effect and safety of Toutongning capsule on migraine. Methods: Eighty-six migraine patients were randomly divided into observation group (46 cases) and control group (40 cases). The observation group was treated with Touttongning capsule 3 times a day for 3 times. The control group was treated with amitriptyline 25 mg 3 times a day, ergotamine 1 mg 3 times a day. The two groups were treated for 4 weeks, comparing the clinical efficacy and adverse reactions. Results: The total effective rate was 40% (87.0%) in the observation group and 27 cases (67.5%) in the control group. There was significant difference between the two groups (P <0.05). No serious adverse reactions were found in either group. Conclusion: Tongtongning capsule is superior to amitriptyline and ergotamine in the treatment of migraine, and it is safe.