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目的观察自制糊剂辅助治疗手足口病的效果。方法选取2012年4月—2013年7月收治的手足口病患儿108例,随机分为对照组和治疗组各54例。两组均给予抗病毒和对症治疗。对照组:将冰硼散喷撒口腔、维生素B_2 5.0 mg口服,3次/d。治疗组:清洁口腔后,将自制糊剂涂抹于口腔疱疹及溃疡处,3次/d,涂药30min内暂缓进食、进水。同时给予有效护理。计量资料采用t检验,计数资料采用x~2检验,P<0.05为差异有统计学意义。结果对照组显效12例,有效22例,无效20例,总有效率62.96%;治疗组显效36例,有效15例,无效3例,总有效率94.44%。两组总有效率比较差异有统计学意义(x~2=15.965,P<0.05)。对照组疱疹消失时间、溃疡愈合时间、口腔疼痛消失时间[(51.23±22.65)、(62.17±31.80)、(46.51±23.82)h]与治疗组[(24.90±9.89)、(44.46±17.13)、(20.82±10.89)h]比较,差异均有统计学意义(t=7.829、3.603、7.208,均P<0.05)。结论自制糊剂辅助治疗手足口病,同时配合有效的护理措施,效果满意,值得临床推广。
Objective To observe the effect of self-made paste in the treatment of hand-foot-mouth disease. Methods A total of 108 children with HFMD who were admitted from April 2012 to July 2013 were randomly divided into control group and treatment group (n = 54). Both groups were given anti-virus and symptomatic treatment. Control group: Spray Bingbing scattered oral, vitamin B_2 5.0 mg orally, 3 times / d. Treatment group: After cleaning the mouth, the homemade paste smear on oral herpes and ulcers, 3 times / d, drug suspension within 30min, water. At the same time give effective care. Measurement data using t test, count data using x ~ 2 test, P <0.05 for the difference was statistically significant. Results In the control group, 12 cases were markedly effective, 22 cases were effective, 20 cases were ineffective and the total effective rate was 62.96%. 36 cases were markedly effective in treatment group, 15 cases were effective and 3 cases were ineffective. The total effective rate was 94.44%. The total effective rate between the two groups was statistically significant (x ~ 2 = 15.965, P <0.05). The time of disappearance of herpes, healing time of ulcer and disappearance of oral pain in control group [(51.23 ± 22.65), (62.17 ± 31.80), (46.51 ± 23.82) h] and control group [(24.90 ± 9.89), (44.46 ± 17.13) (20.82 ± 10.89) h], the differences were statistically significant (t = 7.829,3.603,7.208, all P <0.05). Conclusion Self-made paste adjuvant treatment of hand, foot and mouth disease, combined with effective care measures, the effect is satisfactory, worthy of clinical promotion.