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胃动素是一种脑-肠肽激素,其主要生理功能是影响胃肠道的运动,并通过神经通路起作用。胃动素分子量为2700,是由22个氨基酸残基组成的直链多肽。常温下胃动素易于降解,但低温下保存,经反复冻融20次,均未见明显降解。目前有关消化道和呼吸道癌症患者血浆胃动素变化的报道甚少,本文介绍两组癌症患者胃动素水平,并对其临床意义加以讨论。 对象与方法 一、一般资料 消化道癌症组29例,男性21例,女性8例,年龄范围为34～79岁,平均64.7岁。其中食管癌7例,胃癌18例,肠癌4例。经手术切除治疗者17例。肝肾功能(除6例未做检查外)均正常。均经B超、钡餐、CT、
Motilin is a brain-gut peptide hormone whose main physiological function is to influence the movement of the gastrointestinal tract and act through the neural pathway. Motilin has a molecular weight of 2,700 and is a linear polypeptide consisting of 22 amino acid residues. Motilin was easily degraded at room temperature, but it was preserved at low temperature. After repeated freezing and thawing for 20 times, no obvious degradation was observed. At present, there are very few reports on changes of plasma motilin in patients with digestive tract and respiratory cancer. This article describes the motilin levels in two groups of cancer patients and discusses its clinical significance. Subjects and methods First, general information 29 cases of digestive tract cancer group, 21 males and 8 females, aged 34 to 79 years old, average 64.7 years old. There were 7 cases of esophageal cancer, 18 cases of gastric cancer, and 4 cases of colon cancer. 17 cases were treated by surgical resection. Liver and kidney function (except 6 cases without examination) were normal. All by B-, barium meal, CT,