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目的:对抗菌药物临床应用中存在的问题及有效对策进行探讨。方法:选取我院在2011年1月-2013年12月使用抗菌药物进行治疗的450例患者,统计分析患者的病历与抗菌药物的使用情况,以分析患者的抗菌药物临床应用的合理性。结果:450例患者中,76例患者存在抗菌药物不合理使用情况,占16.9%。在本次探究过程中,患者会用预防性抗菌药物的患者较多,且患者的治疗疗程较长。抗菌药物的联用,能够预防感染的发生,降低感染的发生率。此外,抗菌药物使用的盲目性、给药次数不当、细菌培养检出率低,输液使用不合理等。结论:在抗菌药物的临床使用过程中,需遵循抗菌药物临床应用指南用药,掌握抗菌药物临床应用指征,提高抗菌药物临床用药的合理性。
Objective: To discuss the problems in clinical application of antibacterial drugs and the effective countermeasures. Methods: We selected 450 patients treated with antibiotics from January 2011 to December 2013 in our hospital, and analyzed the patient’s medical history and the use of antibacterials to analyze the rationality of the clinical application of antibacterials. Results: Of the 450 patients, 76 patients had an unreasonable use of antimicrobial agents, accounting for 16.9%. In the course of this inquiry, patients were more likely to use prophylactic antibiotics, and their treatment was longer. Antibacterials, can prevent the occurrence of infection, reduce the incidence of infection. In addition, the blind use of antibacterial drugs, improper dosing, detection rate of bacterial culture is low, irrational infusion and so on. Conclusion: In the course of clinical use of antibacterial drugs, it is necessary to follow the guidelines of clinical application of antibacterial drugs, to grasp the indications of clinical application of antibacterial drugs and to improve the rationality of clinical use of antibacterial drugs.