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目的：为了阐明肝动脉化疗栓塞后碘油在肝癌内选择性聚积、持续存留和逐渐消失的规律。方法：用血管造影和ＣＴ对照分析５８例肝癌肝动脉化疗栓塞后碘油在肝肿瘤内的初期聚积特点，用ＣＴ动态观察２８例碘油在肝癌内的存留和消失时间，同时与１２例栓后切除标本行病理对照研究。结果：碘油能选择性聚积于多血供的肝癌内，聚积量与肿瘤血供有关。少血供肝癌无或少有碘油聚积。碘油选择性聚积并持续存留的部位是肿瘤栓后坏死区，一般存留２～６月甚至更长，伴肿瘤明显缩小；碘油虽能选择性聚积但逐渐消失的部位是肿瘤栓后存活区，一般在１～２月消失，肿瘤缩小不明显或反增大。少量碘油在非癌肝实质一般２周消失。结论：碘油能选择性聚积并持续存留于栓后所致的肿瘤坏死区。ＣＴ随访可判断疗效和确定再次治疗时间。
Objective: To elucidate the regular accumulation, persistence, and gradual disappearance of lipiodol in hepatocellular carcinoma after transcatheter arterial chemoembolization. Methods: The initial accumulation characteristics of lipiodol in liver tumor after hepatic artery embolization in 58 patients with hepatocellular carcinoma were analyzed by angiography and CT. The persistence and disappearance time of 28 cases of lipiodol in liver cancer were dynamically observed by CT. After resection specimens pathological control study. RESULTS: Lipiodol selectively accumulates in the hepatocellular carcinoma with multiple blood supply, and the amount of accumulation is related to the blood supply of the tumor. Less blood for liver cancer with no or little accumulation of iodized oil. The site of selective accumulation of iodized oil and its persistence is the necrotic area after tumor suppository, which generally stays for 2 to 6 months or even longer, with marked tumor shrinkage. The site where the lipiodol can accumulate selectively but gradually disappears is the survival area after tumor suppository , generally disappeared in January to February, tumor shrinkage is not obvious or reverse increase. A small amount of lipiodol disappeared in non-cancerous liver parenchyma for 2 weeks. Conclusion: Lipiodol can accumulate selectively and persist in the tumor necrosis area caused by suppository. CT follow-up can determine the efficacy and determine the time for retreatment.