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成人急性白血病194例随机分为二组治疗,一组RAP方案(柔红霉素、阿糖胞苷和强的松联合)。另一组RAP+T方案(RAP方案+硫乌嘌呤)。RAP组101例,37％达到缓解:RAP+T组93例,35％缓解。二组生存期及缓解期相似。二组在白血病类型及年龄组方面都不优于其他病例组。用RAP方案治疗失败者有9例用其他化疗获得缓解,而RAP+T方案治疗无效者改用其他化疗后没有1例缓解。
A total of 194 adult patients with acute leukemia were randomly divided into two groups. One group received RAP regimen (daunorubicin, cytarabine and prednisone). Another group of RAP + T regimens (RAP regimen + sulfathioprine). In the RAP group, 101 cases achieved remission in 37%, 93 cases in the RAP + T group, and 35% were relieved. Two groups of similar survival and remission. The two groups were not superior to other cases in terms of leukemia type and age group. Nine patients who failed to respond to RAP regimen were treated with other chemotherapies, whereas none of them responded to RAP + T regimen after switching to other regimens.