This paper presents a simulator model of a marine diesel engine based on physical, semi-physical, mathematical and thermodynamic equations, which allows fast predictive simulations. The whole engine system is divided into several functional blocks: cooling, lubrication, air, injection, combustion and emissions. The sub-models and dynamic characteristics of individual blocks are established according to engine working principles equations and experimental data collected from a marine diesel engine test bench for SIMB Company under the reference 6M26SRP1. The overall engine system dynamics is expressed as a set of simultaneous algebraic and differential equations using sub-blocks and S-Functions of Matlab/Simulink. The simulation of this model, implemented on Matlab/Simulink has been validated and can be used to obtain engine performance, pressure, temperature, efficiency, heat release, crank angle, fuel rate, emissions at different sub-blocks. The simulator will be used, in future work, to study the engine performance in faulty conditions, and can be used to assist marine engineers in fault diagnosis and estimation(FDI) as well as designers to predict the behavior of the cooling system, lubrication system, injection system, combustion, emissions, in order to optimize the dimensions of different components. This program is a platform for fault simulator, to investigate the impact on sub-blocks engine’s output of changing values for faults parameters such as: faulty fuel injector, leaky cylinder, worn fuel pump, broken piston rings, a dirty turbocharger, dirty air filter, dirty air cooler, air leakage, water leakage, oil leakage and contamination, fouling of heat exchanger, pumps wear, failure of injectors(and many others).