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对92例冠心病患者多项生化指标进行测定,观察患者服用中药“心脑维新”前后体内脂质过氧化速率、微量元素及脂质代谢的变化。结果:疗后红细胞超氧化物质歧化酶(SOD)比活性,高密度脂蛋白胆固醇(HDL-CH)含量明显提高(P值均<0.001),血浆过氧化脂质(LPO)、血清总胆固醇(T-ch)及甘油三酯(TG)浓度、血清异柠檬酸脱氢酶(ICD)活性、血浆微量元素(Cu,Zn,Fe)含量显著下降(P值均<0.05)。提示该中药具有明显的抑制脂质过氧化和抗衰老作用,并能调节微量元素及脂质代谢。
A number of biochemical indexes were measured in 92 patients with coronary heart disease. The changes of lipid peroxidation rate, microelement and lipid metabolism in patients before and after taking “Xinxin Wei” were observed. Results: The activity of erythrocyte superoxide dismutase (SOD) and the content of high density lipoprotein cholesterol (HDL-CH) in erythrocytes were significantly increased after treatment (P all <0.001), plasma lipid peroxidation (LPO), serum total cholesterol T-ch), triglyceride (TG), serum ICC, and Cu, Zn and Fe were significantly decreased (all P <0.05). Prompted the traditional Chinese medicine has obvious inhibition of lipid peroxidation and anti-aging effects, and can regulate trace elements and lipid metabolism.