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正电子发射断层摄影(PET)可利用葡萄糖同型物~(18)氟脱氧葡萄糖(~(18)FDG)作为示踪剂以评价细胞的代谢。已证实包括结直肠癌在内的某些肿瘤细胞的葡萄糖代谢增高。大量研究指出~(18)FDGPET对检出原发及复发的结直肠癌具有潜在的巨大作用。本研究以之作为对肝内病灶鉴别良恶性的方法,与CT、CT门脉造影进行比较,对其检出肝外复发能力与CT比较。 病人与方法:疑为结直肠癌肝脏复发病人24例,男15,女9,平均年龄62±11岁。原发肿瘤均已切除,其中7例因治疗肝转移已行部分肝切除。本检查在末次手术1年后施行。PET、CT、CT门脉造影各间隔2月施行。扫描前至少禁食4小时,连续图像按需可包括整个胸,腹及盆腔。静脉注入~(18)FDG
Positron emission tomography (PET) can use glucose isoforms ~ (18) fluorodeoxyglucose (~(18)FDG) as a tracer to evaluate cell metabolism. Increased glucose metabolism has been demonstrated in some tumor cells including colorectal cancer. A large number of studies have pointed out that ~(18)FDGPET has a potentially huge effect on the detection of primary and recurrent colorectal cancers. This study used it as a method to differentiate benign from malignant lesions in intrahepatic lesions. Comparing it with CT and CT portography, the ability to detect extrahepatic recurrence was compared with CT. PATIENTS AND METHODS: Twenty-four patients with suspected liver recurrence of colorectal cancer, male 15, female 9, mean age 62 ± 11 years old. The primary tumors had been removed, and 7 of them had undergone partial hepatectomy for liver metastases. This test is performed one year after the last surgery. PET, CT, and CT portography were performed at intervals of 2 months. At least 4 hours before the scan, the continuous image can include the entire chest, abdomen and pelvis as needed. Intravenous injection of ~(18)FDG