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目的了解合肥工业大学新生接种乙型肝炎疫苗后的远期免疫效果。方法 2007年10月选择合肥工业大学2007级符合乙型肝炎疫苗接种条件的新生80名为接种组,于2007年10月15日起进行全程乙型肝炎疫苗接种;同期选择2007级符合乙型肝炎疫苗接种条件但不同意接种的新生80名为对照组。两组均于2011年5月20日毕业体检时进行乙型肝炎五项检测进行比较。计数资料采用χ2检验,P<0.05为差异有统计学意义。结果接种组乙型肝炎表面抗体(HBs-Ab)阳性率为82.50%,乙型肝炎表面抗原(HBs-Ag)阳性率为3.75%;对照组HBs-Ab阳性率为22.50%,HBs-Ag阳性率为12.50%。两组比较差异均有统计学意义(均P<0.05)。结论大学新生入学时符合乙型肝炎疫苗接种者进行乙型肝炎疫苗接种是非常必要的。
Objective To understand the long-term immunization of Hefei University of Technology freshmen vaccinated with hepatitis B vaccine. Methods In October 2007, 80 freshmen who were eligible for Hepatitis B vaccination in Hefei University of Technology were selected as inoculation group and were vaccinated for Hepatitis B on October 15, 2007. In the same period, Hepatitis B Vaccination conditions but did not agree to vaccinate 80 newborn students as control group. Two groups were on May 20, 2011 graduation examination for hepatitis B five tests were compared. Count data using χ2 test, P <0.05 for the difference was statistically significant. Results The positive rate of HBs-Ab in vaccinated group was 82.50%, the positive rate of HBs-Ag in HBsAg-positive group was 3.75%. The positive rate of HBs-Ab in control group was 22.50% The rate is 12.50%. The differences between the two groups were statistically significant (P <0.05). Conclusions It is very necessary for freshmen to meet the hepatitis B vaccination for hepatitis B vaccination.