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目的:研究狗脊生、制品的正丁醇提取物的抗骨质疏松作用。方法:将SD雌性大鼠切除卵巢造成骨质疏松动物模型,用狗脊生、制品的正丁醇提取物溶液灌胃给药研究其对卵巢去势大鼠的抗骨质疏松作用。结果:狗脊制品正丁醇提取物对卵巢去势大鼠具有显著的抗骨质疏松作用,狗脊生品正丁醇提取物对卵巢去势大鼠具有一定的抗骨质疏松作用。结论:狗脊生、制品的正丁醇提取物具有一定的抗骨质疏松的作用。
OBJECTIVE: To study the anti-osteoporosis effect of n-butanol extract from dog’s vertebra and products. Methods: SD female rats were ovariectomized and induced osteoporosis animal model. The anti-osteoporosis effect of ovariectomized rats was observed by intragastric administration of n-butanol extract solution of dog vertebra and products. Results: The n-butanol extract of dogbone products had significant anti-osteoporosis effect on ovariectomized rats. The n-butanol extract of dog’s spinal products had anti-osteoporosis effect on ovariectomized rats. CONCLUSION: The n-butanol extract of dog’s vertebra and products has certain anti-osteoporosis effect.