摘要目的应用心脏MR成像、心肌损伤血清标志物以及病理镜检量化特定体积与大小的微栓子对已有急性心肌梗死的模型猪的心肌活性、左室功能以及心肌灌注的影响。材料与方法 X线透视检查获得学院批准。16头猪行冠状动脉左前降支阻塞90 min后再灌注(单次缺血损伤),其中8头猪再行冠状动脉栓塞术(32 mm3,40~120μm微栓子)(2次缺血损伤),另8头猪作为对照组。记录心脏MRI结果(心肌活 Abstract Objective To evaluate the effects of cardiac MR imaging, myocardial injury serum markers and pathological microscopy on myocardial activity, left ventricular function and myocardial perfusion in a porcine model of acute myocardial infarction (AMI) with micro-emboli of specific volume and size. Materials and Methods X-ray examination was approved by the college. Twenty-six pigs underwent coronary artery embolization (32 mm3, 40-120 μm) with ischemic insult (ischemia-reperfusion injury) after 90 min of occlusion of left anterior descending coronary artery in 16 pigs. ), Another 8 pigs as control group. Record cardiac MRI results (myocardial viability