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目的:观察加味茵陈蒿汤联合思美泰注射液治疗病毒性肝炎高胆红素血症的临床疗效。方法:68例病毒性肝炎高胆红素血症患者,随机分为对照组30例和治疗组38例。对照组采用西医常规综合治疗,治疗组在对照组治疗的基础上使用口服加味茵陈蒿汤联合思美泰注射液静脉滴注治疗。观察治疗前后胆红素变化。结果:治疗2周、4周后2组总胆红素均显著下降,与治疗前比较,差异均有显著性意义(P<0.05)。治疗组治疗2周及4周后总胆红素下降幅度均大于对照组(P<0.05)。治疗组总有效率为89.5%,对照组为66.7%,2组比较,差异有显著性意义(P<0.05)。结论:加味茵陈蒿汤联合思美泰注射液是治疗病毒性肝炎高胆红素血症的一种有效的方法。
Objective: To observe the clinical effects of Modified Yinchenhao Decoction combined with Smectite Injection in treating viral hepatitis with hyperbilirubinemia. Methods: Sixty-eight patients with viral hepatitis with hyperbilirubinemia were randomly divided into control group (n = 30) and treatment group (n = 38). The control group was treated by conventional western medicine. The treatment group was treated with intravenous infusion of Yinchenhao Decoction combined with Smectite Injection on the basis of the control group. Bilirubin changes observed before and after treatment. Results: The levels of total bilirubin in two groups decreased significantly after treatment for two weeks and four weeks, which were significantly different from those before treatment (P <0.05). The decrease of total bilirubin in treatment group after 2 weeks and 4 weeks were both greater than those in control group (P <0.05). The total effective rate was 89.5% in the treatment group and 66.7% in the control group. There was significant difference between the two groups (P <0.05). Conclusion: Modified Yinchenhao decoction combined with Smectite injection is an effective method for the treatment of viral hepatitis with hyperbilirubinemia.