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目的 :实验研究板蓝根凝集素对小鼠胸腺组织发育和胸腺细胞增殖的作用。方法 :用生物化方法提取板蓝板凝集素 ,以昆明种小鼠为观察对象 ,用 0 .0 54mg/ kg/ d剂量板蓝根凝集素灌胃 ,连续 30天 ,采用组织切片方法 ,光学显微镜检测胸腺皮质与髓质细胞 ,并进行生物学统计。结果 :与对照组比较 ,实验组小鼠胸 /体比值 P<0 .0 5,胸腺皮质与髓质胸腺细胞密度 P<0 .0 1,细胞直径 >0 .0 5。结论 :实验证明板蓝根凝集素对小鼠胸腺的发育和胸腺细胞的增殖可能具有促进作用 ,对维持胸腺微环境可能起间接作用
Objective : To study the effects of Radix Isatidis lectin on thymus tissue development and thymocyte proliferation in mice. METHODS: The blu-blue plate agglutinin was extracted by biological method. Kunming mice were used as the observation objects. Radix isatidis lectin was given at a dose of 0.05 mg/kg/d for 30 days. The tissue section method was used for optical microscopy. Thymic cortex and medulla cells, and biological statistics. RESULTS: Compared with the control group, the ratio of chest to body of the experimental group P 0. 05, the density of thymus cortex and medulla thymocytes P 0. 01, cell diameter > 0. 05. Conclusion : Experiments show that Radix Isatidis lectin may promote the development of thymus and thymocyte proliferation in mice and may play an indirect role in maintaining the thymus microenvironment.