骨细胞长久以来都被看作是一种终末分化的、代谢惰性的、深埋在骨基质之中的占位细胞,并不具有重要的生理作用和功能。然而近些年的研究发现,骨细胞是一种活跃的多功能细胞,参与机体诸多生物学过程的调控。骨细胞的生物学功能可以大致归纳为以下六类:调节骨重建平衡、感知和转导力学刺激、参与机体的神经–内分泌调节、与肌肉组织有密切的相互作用、降解与合成骨基质及调控骨组织内储存的钙和其他生物活性物质。 Osteocytes have long been considered as a terminally differentiated, metabolically inert, space-occupying cell that is embedded in the bone matrix and does not have important physiological roles and functions. However, in recent years, the study found that osteocytes is an active multi-functional cell involved in many biological processes in the body. The biological function of osteocytes can be summarized into the following six categories: the regulation of bone remodeling balance, sense and transduction mechanics stimulation, involved in the body’s neuroendocrine regulation, and muscle tissue have a close interaction, degradation and synthesis of bone matrix and regulation Calcium and other bioactive substances stored in bone tissue.