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邻硝基氯苯是亲肝毒物,通过对洛阳化工四厂,接触该毒物的97名工人(其中女工31名),连续进行12年的动态观察结果,支持肝肿的阳性率逐年增加P<0.05,而肝肿大与有毒车间空气浓度呈密切相关P<0.05。肝功三项指标的阳性率也随空气浓度的增加而增高P<0.05。 在目前中毒性肝病没有特异诊断指标的情况下,我们根据接触亲肝毒物作业工龄、临床表现、肝功损害程度,在排除其他病因引起的肝病情况下,即可诊断中毒性肝病,有其他异常及时对症处理,这与有关报导一致。
O-nitrochlorobenzene is a pro-hepatotoxic agent. By observing the dynamic observation of 97 workers (including 31 females) exposed to No. 4 Luoyang Chemical Plant and the toxicants for 12 consecutive years, the positive rate of supporting hepatomegaly increased year by year (P < 0.05, and hepatomegaly and toxic plant air concentration was closely related to P <0.05. The positive rate of three indicators of liver function also increased with air concentration increased P <0.05. In the current no specific diagnostic indicators of toxic liver disease cases, we are exposed to pro-hepatotoxic drugs based on length of service, clinical manifestations, liver damage, excluding other causes of liver disease, you can diagnose toxic liver disease, there are other abnormalities Timely symptomatic treatment, which is consistent with the relevant reports.