报告１９７８年～１９９３年收治的１０例肾上腺皮质癌，其中有内分泌功能性６例，无内分泌功能性４例。有内分泌功能性肾上腺皮质癌有典型的临床表现，如Ｃｕｓｈｉｎｇ′ｓ综合征、性征异常表现。无内分泌功能性肿瘤为腺外表现：如急性腹痛、高血压等。尿１７－羟、１７－酮、皮质醇测定、ＣＴ及Ｂ超检查均有助于诊断。肿瘤越大恶性可能性越大。手术是唯一的治疗方法。因该病早期诊断困难，特别是无功能性肿瘤，因而预后差。 Reported 10 cases of adrenocortical carcinoma admitted from 1978 to 1993, including 6 cases of endocrine function and 4 cases of endocrine function. Endocrine functional adrenocortical carcinoma has typical clinical manifestations such as Cushing’s syndrome and abnormal sexuality. Non-endocrine functional tumors are extra-adrenal manifestations such as acute abdominal pain and hypertension. Urinary 17-hydroxyl, 17-keto, cortisol determination, CT and B-ultrasound all contribute to the diagnosis. The larger the tumor, the greater the likelihood of malignancy. Surgery is the only treatment. Because of the difficulty of early diagnosis of the disease, especially non-functional tumors, the prognosis is poor.