幽门管溃疡有时被误认为位于十二指肠,且很少是恶性溃疡,现报告幽门管恶性溃疡1例。患者女,65岁。因间歇性上腹部疼痛10余年,加重伴恶心、呕吐及体重下降15ｄ,于1996年11月5日入院。上腹痛常在劳累及进油腻食物后加重,并向右肩部放射。体检:腹平软,右上腹压痛明显,莫菲征阳性。 Pyloric canal ulcers are sometimes mistaken for the duodenum and are rarely malignant, and one case of pyloric canal malignancy has been reported. Female patient, 65 years old. Due to intermittent upper abdominal pain for more than 10 years, aggravated with nausea, vomiting and weight loss 15d, admitted to hospital on November 5, 1996. Upper abdominal pain often worsens after being tired and into greasy food and radiates to the right shoulder. Physical examination: abdominal plain soft, right upper quadrant tenderness, Murphy sign positive.