副猪嗜血杆菌是常规猪上呼吸道的一种共栖菌 ,它可在特定条件下侵入机体而引起严重的全身性疾病 ,以纤维素性多发性浆膜炎、关节炎和脑膜炎为特征。副猪嗜血杆菌侵入全身的有关因素仍然很不清楚。然而 ,我们已知的副猪嗜血杆菌主要研究进展包括 :(1)建立了具有种特异性的PCR诊断方法用于检测临床样品中的副猪嗜血杆菌 ;(2 )利用rep -PCR技术进行猪场内和猪场间分子流行病学的研究 ;(3)提出了另一种血清分型技术 ;(4 )提出并测试了一种新的活体动物模型用于致病性和毒力研究 ,以及 (5 )使用低剂量的有毒力副猪嗜血杆菌活菌在控制下感染青年猪的方法来降低发病猪场保育猪的死亡率 Haemophilus parasuis, a common fungus in the upper respiratory tract of conventional pigs, can invade the body under specific conditions and cause serious systemic disease characterized by multiple serosal fibrosis, arthritis and meningitis. The related factors of Haemophilus parasuis invade the whole body remain unclear. However, the main research progresses of Haemophilus parasuis which we know include: (1) establishing a species-specific PCR diagnostic method for detection of Haemophilus parasuis in clinical samples; (2) using the rep-PCR technique (3) proposed another serotyping technique; (4) proposed and tested a new live animal model for pathogenicity and virulence Research, and (5) the use of low doses of virulent Haemophilus parasuis to infect young pigs under control to reduce the mortality of nursery pigs in affected farms