论文部分内容阅读
目前多种维生素制剂包括片剂、糖浆和胶囊剂普遍存在着维生素A含量下降严重问题。尽管在生产上采取多投料(140～160％) 办法,其有效期也仅维持一年。影响维生素A含量下降原因很多,但主要是空气,其次是水分、光线和温度。为了制备VA稳定性良好的多维制剂,必须选择一种合适的剂型和合理的处方及工艺。我们选择了软胶囊剂,它具有密封、避光,不易受热的特点,是VA较合适的剂型。按照BPC(1973年版)规格,我们着手多种维生素软胶囊的试制工作。本文对胶囊稀释剂、混悬液抗氧剂、稳定剂和胶囊遮色剂
At present, a variety of vitamin preparations, including tablets, syrups and capsules, the prevalence of vitamin A serious problem of declining. Although the production of more feeding (140 ~ 160%) approach, its validity is only maintained for one year. There are many reasons for the decline in vitamin A content, but mainly air, followed by moisture, light and temperature. In order to prepare multi-dimensional preparations with good VA stability, an appropriate dosage form and reasonable prescription and process must be selected. We chose the soft capsule, it has a sealed, dark, not easy to heat the characteristics of VA is the more appropriate form. According to the BPC (1973 version) specifications, we started a variety of vitamin soft capsule trial. This article on capsule diluents, suspensions antioxidants, stabilizers and capsules opacifiers