论文部分内容阅读
结合药理和化学方法对小承气汤、厚朴大黄汤及厚朴三物汤三方泻下作用物质基础进行初步研究。药理研究结果显示：三方均明显增加小鼠大肠湿重．其泻下作用强度与所含大黄成正比，小承气汤效价最高；其拆方研究表明．影响泻下作用的最显著因素为大黄，次显著因素为枳实。三方化学成分研究结果显示：小承气汤中结合蒽醌含量最高。表明三方均具有明显泻下作用，其效价差异的物质基础与方中所含大黄及其煎出的结合蒽醌含量有关。
Combining pharmacological and chemical methods, a preliminary study was conducted on the material basis of the three-sided diarrhea effect of Xiaochengqi Decoction, Houpu Dahuang Decoction, and Houpu Sanwu Decoction. The results of pharmacological studies showed that all three groups significantly increased the wet weight of mice. The strength of the diarrhea is proportional to the contained rhubarb, Xiaochengqitang has the highest titer; The most significant factor affecting the effect of diarrhea was rhubarb, and the second most significant factor was compaction. The results of triphasic chemical composition study showed that the content of combined germanium in Xiaochengcheng Decoction was the highest. It was shown that the three parties all had a significant purgative effect, and the material basis for the difference in titer was related to the content of rhubarb contained in the formula and its combined fructose content.