论文部分内容阅读
目的:探讨儿童肺炎支原体感染与微量元素之间的因果关系,为微量元素在儿童肺炎支原体感染的发生发展提供数据支持。方法:将2013年1月~2014年11月收治的肺炎支原体感染患儿287例,男169例,女118例,按照年龄段分为4组,其中>0岁≤1岁组75例,>1岁≤2岁组87例,>2岁≤4岁组91例,>4岁≤7岁组44例;同时选取同期年龄阶段相同的健康体检儿287例作为对照组。采用5通道原子吸收光谱法对患儿进行Cu,Zn,Se,Mg,Fe 5种元素进行检测。结果:肺炎支原体感染组患儿Zn、Fe、Se含量均明显低于对照组,两组间相比具有统计学差异(P<0.05);Cu高于对照组,Mg低于对照组,但两组间相比不具有统计学差异(P>0.05);不同年龄段儿童肺炎支原体感染的微量元素显示,>0岁≤1岁组Zn、Fe、Se含量均低于对照组(P<0.05);>1岁≤2岁组Zn、Fe含量均低于对照组(P<0.05);>2岁≤4岁组Zn、Se含量均明显低于对照组(P<0.05),>4岁≤7岁组Se含量均明显低于对照组(P<0.05)。结论:儿童肺炎支原体感染的发生与Se、Mg、Fe、Zn 4种元素的缺乏有关,早期Se、Fe、Zn缺乏严重,随着年龄的增长,缺Se的情况未能缓解,而其他两种元素水平有所增加。检测5种元素的含量对儿童肺炎支原体感染的诊断和治疗有一定的指导作用。
Objective: To explore the causal relationship between mycoplasma pneumoniae infection and trace elements in children, and provide data support for the occurrence and development of children’s Mycoplasma pneumoniae infection with trace elements. Methods: From January 2013 to November 2014, 287 children with Mycoplasma pneumoniae infection, 169 males and 118 females, were divided into 4 groups according to their ages, of which 75 were> 0 years old and ≤1 years old, and> There were 87 cases of 1-year-old ≤2-year-old group, 91 cases of> 2-year-old≤4-year-old group, and 44 cases of> 4-year-old≤7-year-old group.At the same time, 287 children with the same age in same age were selected as control group. Five-channel atomic absorption spectrometry was used to detect Cu, Zn, Se, Mg and Fe in children. Results: The contents of Zn, Fe and Se in children with Mycoplasma pneumoniae infection were significantly lower than those in the control group (P <0.05), while Cu was higher than that in the control group The trace elements of Mycoplasma pneumoniae infection in children of different ages showed that the contents of Zn, Fe and Se in the group of 0-year-old ≤1 year-old were lower than that of the control group (P <0.05) (P <0.05). The contents of Zn and Se> 2 years old and ≤4 years old were significantly lower than those of the control group (P <0.05),> 4 years old ≤ Se content in 7-year-old group was significantly lower than that in control group (P <0.05). Conclusion: Mycoplasma pneumoniae infection is related to the deficiency of Se, Mg, Fe and Zn in children. The early Se, Fe and Zn lacks seriously. With age, the lack of Se can not be alleviated, while the other two Elemental levels have increased. Detection of five elements in children with Mycoplasma pneumoniae infection diagnosis and treatment have a guiding role.