临床资料本文总结1978～1985年本院诊治67例急性非淋巴细胞白血病(ANLL)未能缓解(即化疗失败)的病例,占同期化疗120例的55.8%.化疗方案 1979年以前 COAP 为首选方案,1980年以后 HOAP 为首选方案,本文两组方案疗效未见明显差异.化疗失败类型分析结合临床表现、血象、髓象及其它有关实验室检查,将失败病例分为三类:Ⅰ类治疗不满1个疗程,迅速死于并发症者14例,Ⅱ类治疗2～3个疗程,病情有改善,而后死于并发症者39例;Ⅲ类治疗虽满3个疗程,因无效而死于并发症者14例.死因分析1.颅内出血(28例次):均与血小板减少有 Clinical data This article summarizes the 67 cases of acute non-lymphocytic leukemia (ANLL) in our hospital from 1978 to 1985, the treatment of refractory cases (accounting for the failure of chemotherapy), accounting for 55.8% of 120 cases of chemotherapy in the same period chemotherapy before 1979 COAP preferred solution , HOAP was the first option after 1980, and there was no significant difference in the curative effect between the two groups.Analysis of the type of failure in chemotherapy combined with clinical manifestations, blood images, medulla, and other related laboratory tests classified the failure cases into three groups: Class I treatment dissatisfaction A course of treatment, rapid death from complications in 14 cases, Ⅱ class of treatment of 2 to 3 courses, the condition improved, and then died of complications in 39 cases; class Ⅲ treatment is full of 3 courses, died of complications due to ineffective Symptoms in 14. Cause of death 1. Intracranial hemorrhage (28 cases): both with thrombocytopenia