论文部分内容阅读
目的了解招标疫苗的安全性和免疫效果,为政府制定和调整防控策略提供科学依据。方法采用流行病学队列研究方法进行,用《流感疫苗安全性及效果效益评价调查表》进行随访调查。用症状出现的反应率作为安全性评价指标,接种效益和效益成本比作为评价效益指标,采用EPIDATA数据库软件进行数据录入,应用SPSS10.0统计软件进行统计学分析,运用卫生经济学评价方法进行成本效益分析。结果老人接种组1人发病,对照组3人发病;学生接种组2人发病,对照组5人发病和11例流感样病例,老年组在接种第3和6个月内,效益成本比分别为1.77:1和2.03:1;学生组在流感疫苗接种第3和6个月内,效益成本比分别为1.2:1和1.3:1,本研究老人有1.70%(7/412)自述局部出现疼痛,1.46%(6/412)局部出现硬结,学生有1.40%(5/356)局部出现疼痛,0.84%(3/356)局部出现发热症状。结论老年人和学生接种流感疫苗,不仅有效预防流感的发生和流行,取得很好的社会经济效益,也是安全可行的.
Objective To understand the safety and immunization effects of bidding vaccines and provide a scientific basis for the government to formulate and adjust its prevention and control strategies. Methods The epidemiological cohort method was used to conduct follow-up investigation with “Influenza Vaccine Safety and Effectiveness Evaluation Questionnaire”. Use the reaction rate of symptom as safety evaluation index, inoculate benefit and benefit cost ratio as index of evaluation benefit, use EPIDATA database software to carry on data input, use SPSS10.0 statistical software to make statistical analysis, use health economics evaluation method to carry on cost Benefit Analysis. Results There were 1 inoculation group and 3 in control group. There were 2 inoculation group, 5 in control group and 11 in flu group. The benefit-cost ratios in the elderly group at 3 and 6 months of inoculation were 1.77: 1 and 2.03: 1 respectively. The cost-benefit ratios of students in the first 3 and 6 months of influenza vaccination were 1.2: 1 and 1.3: 1, respectively. In the study, 1.70% (7/412) , 1.46% (6/412) showed partial induration. There were 1.40% (5/356) local pain in students and 0.84% (3/356) local fever symptoms. Conclusion It is safe and feasible to vaccinate the elderly and students against influenza, not only to effectively prevent the occurrence and prevalence of influenza, but also to obtain good social and economic benefits.