众所周知,当重复感染时,血吸虫的脊椎动物宿主会对之产生被称为“伴随免疫”的抗性。而这种抗性产生的原因尚有争论。本文通过曼氏血吸虫的自然感染和人工感染黑家鼠实验,对该问题提供一些数据。材料和方法曼氏血吸虫来源于西印度瓜德罗普自然感染的黑家鼠。野生黑家鼠捕自瓜德罗普,并经实验室繁殖。每只黑家鼠 It is well known that vertebrate hosts of schistosomes develop resistance called “concomitant immunity” when they are repeatedly infected. The reason for this resistance is still controversial. In this paper, the natural infection of Schistosoma mansoni and artificial infection of black house mice experiments, to provide some data on the issue. Materials and Methods Schistosoma mansoni was derived from the naturally infected black house mouse of Guadeloupe, West Indies. Wild black housefly caught in Guadeloupe, and laboratory breeding. Every black house mouse