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目的观察硫辛酸联合2%胰岛素溶液与磺胺嘧啶银乳膏外用治疗糖尿病足溃疡的疗效,评价其临床应用价值。方法收集安阳市人民医院2010年6月至2012年12月糖尿病足溃疡住院患者60例,按编号随机分为两组,每组30例,对照组给予硫辛酸治疗,治疗组在对照组给药基础上联合2%胰岛素溶液与磺胺嘧啶银乳膏外用。结果经3周治疗后对照组有效率为73.3%,治疗组有效率为96.7%,差异具有统计学意义(P<0.05)。结论硫辛酸联合2%胰岛素溶液与磺胺嘧啶银乳膏外用治疗糖尿病足溃疡疗效肯定,值得临床推广。
Objective To observe the effect of lipoic acid combined with 2% insulin solution and sulfadiazine silver cream on the treatment of diabetic foot ulcer, and to evaluate its clinical value. Methods Sixty patients with diabetic foot ulcer were collected from Anyang People’s Hospital from June 2010 to December 2012. The patients were randomly divided into two groups according to the serial number, 30 cases in each group. The control group was treated with lipoic acid. The treatment group was given the control group Based on the combination of 2% insulin solution and silver sulfadiazine topical cream. Results After 3 weeks of treatment, the effective rate of the control group was 73.3%, and the effective rate of the treatment group was 96.7%. The difference was statistically significant (P <0.05). Conclusions Lipoic acid combined with 2% insulin solution and sulfadiazine silver cream for the treatment of diabetic foot ulcers affirmative effect, worthy of clinical promotion.