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体外抗菌实验表明 ,肺毒清颗粒剂对人葡萄球菌、不动杆菌、表皮葡萄球菌、金黄色葡萄球菌、短小芽孢杆菌、链球菌、洋葱假单孢杆菌等有较强的抑菌作用。 MIC为 12 .5～18.8mg/ m l体内抗菌作用表明 ,肺毒清颗粒剂 42 .0 g/ kg剂量组对金黄色葡萄球菌和肺炎克雷百氏菌感染小鼠具有明显的保护作用 (P<0 .0 1和 P<0 .0 5 )。体内抗病毒试验表明 ,肺毒清颗粒剂 7.0 g/ kg、2 1.0 g/ kg和 42 .0 g/ kg剂量组对 H1 N1 病毒感染小鼠死亡具有明显的保护作用 (P<0 .0 0 5 ) ,并能降低H1 N1 病毒感染小鼠肺指数值 (P<0 .0 1) ,肺指数抑制率为2 6 %、30 %、31%。
Antibacterial experiments in vitro showed that Feiduqing granules had strong antibacterial activity against Staphylococcus aureus, Acinetobacter, Staphylococcus epidermidis, Staphylococcus aureus, Bacillus pumilus, Streptococcus, and Pseudomonas cepacia. The antibacterial effect of MIC of 12.5~18.8mg/ml showed that the 40.0g/kg dose of Feiduqing granule had obvious protective effect on Staphylococcus aureus and Klebsiella pneumoniae infected mice. <0 .0 1 and P <0 .0 5 ). In vivo antiviral tests showed that the doses of Fulingqing granules 7.0 g/kg, 2 1.0 g/kg and 42.0 g/kg had obvious protective effects on the death of H1N1 virus-infected mice (P<0. 0 5), and can reduce the lung index value of H1N1 virus-infected mice (P <0. 01), and the lung index inhibition rate is 26%, 30%, 31%.