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选择23例发病<72h的T2DM脑梗死患者;对照组29例发病<72h的非糖尿病脑梗死患者,予金纳多注射液10ml加入5%葡萄糖液250ml中静脉滴注,每日1次,14d为1个疗程。对每个病例均作头部磁共振扫描。酶免法(EL-LISA)测定患者血浆IL-6和CRP的变化。结果:金纳多治疗T2DM患者脑卒中后缄默症组7天后,患者血浆IL-6和CRP比对照组明显增高(P<0.05)。患者15天左右能讲简单字词,比对照组患者延迟5天。结论:T2DM脑卒中后缄默症与炎症反应有关。
Twenty-three T2DM patients with onset of <72h were enrolled in this study. Twenty-nine patients with non-diabetic cerebral infarction with onset of <72h were given intravenous drip of Jinnindo injection 10ml into 250ml of 5% dextrose solution once daily for 14 days For a course of treatment. For each case for head MRI. Changes of plasma IL-6 and CRP in patients by enzyme-linked immunosorbent assay (EL-LISA). Results: The level of IL-6 and CRP in plasma of patients with T2DM was significantly higher than that of the control group (P <0.05). Patients can speak simple words in about 15 days, 5 days later than the control group patients. Conclusions: Mutations in the pathogenesis of T2DM after stroke are related to inflammation.