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目的研究大果榕Ficus auriculata茎的化学成分。方法运用硅胶柱色谱、Sephadex LH-20凝胶柱色谱,以及制备薄层色谱等方法分离纯化,通过波谱数据和理化性质鉴定结构。结果从大果榕茎95%乙醇提取物中分离得到14个化合物,分别鉴定为6β-羟基豆甾-4-烯-3-酮(1)、6α-羟基豆甾-4-烯-3-酮(2)、豆甾-4-烯-3-酮(3)、3β-羟基豆甾-5-烯-7-酮(4)、豆甾-4-烯-3,6-二酮(5)、麦角甾醇过氧化物(6)、(20S)-3-oxo-20-hydroxytaraxastane(7)、伞形香青酰胺(8)、金色胡椒酰胺乙酸酯(9)、palmarumycin BG1(10)、7-羰基-脱氢枞酸(11)、松柏醛(12)、S-(+)-dehydrovomifoliol(13)、4-羟基-3-甲氧基苯甲酸(14)。结论化合物2、5、7~13为首次从该属植物中分离得到,所有化合物均为首次从该植物中分离得到。
Aim To study the chemical constituents of Ficus auriculata stems. Methods The compounds were separated and purified by silica gel column, Sephadex LH-20 column chromatography and preparative thin layer chromatography. Their structures were elucidated by spectral data and physico-chemical properties. Results Fourteen compounds were isolated from the 95% ethanol extract of the large fruit ficus and identified as 6β-hydroxysteroid-4-en-3-one (1), 6α- (3), 3β-hydroxystilbene-5-en-7-one (4), stigmastan-4-ene-3,6-dione 5), ergosterol peroxide (6), (20S) -3-oxo-20-hydroxytaraxastane (7), umbelliferin (8), aprotinin acetate (9), palmarumycin BG1 ), 7-carbonyl-dehydroabietic acid (11), cypressin (12), S - (+) - dehydrovomifoliol (13) and 4-hydroxy-3-methoxybenzoic acid (14). Conclusions Compounds 2, 5 and 7 ~ 13 were isolated from this genus for the first time, and all the compounds were isolated from this plant for the first time.