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本文总结了54例自身免疫性溶血性贫血(AIHA)与Coombs试验的关系。54例中直接Coombs试验阳性者37例(68.5%),阴性者17例(31.5%)。Coombs试验阴性患者其溶血的严重程度与Coombs试验血清效价的倍数无关,其主要原因是Ig的种类不同。
This article summarizes the relationship between 54 cases of autoimmune hemolytic anemia (AIHA) and Coombs test. Of the 54 cases, 37 (68.5%) were positive for direct Coombs test and 17 (31.5%) were negative. The degree of hemolysis in Coombs-test-negative patients is independent of the Coombs test serum titer multiplier, mainly due to the different Ig species.