论文部分内容阅读
目的:分析不同剂量的右美托咪定复合舒芬太尼与丙泊酚对肝癌患者射频消融麻醉中血流动力学参数的影响。方法:选取2013年1月—2014年10月间收治的行肝癌射频消融手术患者60例作为研究对象,按照数字随机法将其分为A组和B组,每组30例;A组患者均给予右美托咪定0.5μg/kg,舒芬太尼0.6μg/kg与丙泊酚注射液1mg/kg诱导麻醉;B组患者均给予右美托咪定0.8μg/kg,舒芬太尼0.6μg/kg和丙泊酚注射液1 mg/kg麻醉诱导;比较两组患者对麻醉中血流动力学参数的影响。结果:A组患者麻醉自主呼吸恢复时间与拔出喉罩时间均短于B组(P<0.05);术后并发症发生率低于B组(P<0.05);镇静效果与血流动力学参数的改善效果均优于B组(P<0.05)。结论:采用低剂量的右美托咪定复合舒芬太尼与丙泊酚对肝癌患者射频消融手术中诱导麻醉的效果较显著,术后恢复时间快,并发症的发生率较低。
Objective: To analyze the effects of different doses of dexmedetomidine combined with sufentanil and propofol on hemodynamic parameters in radiofrequency ablation of liver cancer patients. METHODS: A total of 60 patients undergoing radiofrequency ablation for liver cancer who were admitted between January 2013 and October 2014 were selected as study subjects. They were divided into group A and group B according to a numerical randomization method, with 30 cases in each group. Dexmedetomidine 0.5 μg/kg, sufentanil 0.6 μg/kg and propofol injection 1 mg/kg were given to induce anesthesia; patients in group B were given dexmedetomidine 0.8 μg/kg, sufentanil 0.6μg/kg and propofol injection 1 mg/kg anesthesia induction; compare the two groups of patients on hemodynamic parameters of anesthesia. RESULTS: The time of spontaneous anesthesia respiration and the duration of pull-out of the laryngeal mask were shorter in group A than in group B (P<0.05); the incidence of postoperative complications was lower than that of group B (P<0.05); sedative effect and hemodynamics The improvement effect of parameters was better than that of group B (P<0.05). CONCLUSIONS: Low-dose dexmedetomidine combined with sufentanil and propofol has a significant effect on induction of anesthesia during radiofrequency ablation of liver cancer patients. The recovery time is faster and the incidence of complications is lower.