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目的:评价中药养阴润肺汤与3 HREZ(S)/6 HRE药物联用在治疗耐多药肺结核患者的临床疗效。方法:选取2010年2月—2013年2月期间收治的耐多药肺结核患者78例,将其分为对照组和治疗组,每组39例;对照组患者给予3 HREZ(S)/6 HRE药物治疗,或者根据药敏试验的结果对用药方案进行适当的调整,于此同时再给予保肝辅助药物治疗;治疗组患者在对照组患者治疗药物的基础上再给予中药养阴润肺汤治疗,用药一疗程后评价两组患者痰菌阴转率、痰培养阴转率、X线胸片吸收好转率、血沉恢复正常率的变化情况。结果:治疗组患者在痰菌阴转率、痰培养阴转率、X线胸片吸收好转率及血沉恢复正常率等方面均优于对照组(P<0.05)。结论:中西医联合用药在治疗耐多药肺结核患者具有较好的疗效。
OBJECTIVE: To evaluate the clinical efficacy of yin yin Runfei decoction combined with 3 HREZ (S) / 6 HRE in the treatment of multidrug-resistant pulmonary tuberculosis patients. Methods: Seventy-eight MDR-TB patients were selected from February 2010 to February 2013, which were divided into control group and treatment group, 39 cases in each. Patients in the control group were given 3 HREZ (S) / 6 HRE Drug treatment, or drug susceptibility testing results based on the appropriate adjustments to the drug regimen, at the same time give the liver supplemented drug treatment; treatment group patients in the control group of patients based on the treatment of Chinese medicine to give yin yin Runfei Tang treatment After treatment, the sputum negative conversion rate, sputum culture negative conversion rate, X-ray absorption improvement rate and erythrocyte sedimentation rate recovery rate in two groups were evaluated after treatment. Results: The patients in the treatment group were better than the control group in sputum negative conversion rate, sputum culture negative conversion rate, X-ray absorption recovery rate and erythrocyte sedimentation rate (P <0.05). Conclusion: The combination of Chinese and Western medicine in the treatment of patients with multidrug-resistant pulmonary tuberculosis has a good effect.