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在抗癌药物日益发展的今天,恶性肿瘤使用化疗的机会日益增多。药学家们虽不遗余力地筛选了近百种抗肿瘤药物,但由于个体差异、肿瘤类型及其不同病期的生物学特性,对化学药物的敏感性各有不同。目前临床医生选用的只是根据药物学家对某种人或动物的肿瘤培养细胞常规筛选的药物,属盲目使用,临床治疗效果常不理想。或者病人已对常规使用的药物产生耐药,而医生仍然使用,故达不到疗效。例如现在都认为烷化剂治疗卵巢恶性肿瘤有效,但并不对所有卵巢肿瘤有效,甚至可完全无效。有的病人使用了多种药物多个疗程仍不免死亡。这是一个妇科肿瘤医生迫切想解决的问题。
In the growing anti-cancer drugs today, the chance of malignant tumors using chemotherapy is increasing. Although pharmacists have spared no efforts to screen nearly a hundred kinds of anti-tumor drugs, they have different sensitivity to chemical drugs due to individual differences, tumor types and their biological characteristics at different stages of disease. At present, clinicians choose drugs that are based on routine screening of tumor cells of a certain kind of human or animal according to the pharmacologists, which are blindly used and the clinical treatment effect is often not satisfactory. Or the patient has been resistant to the commonly used drugs, and the doctor still use, it is not effective. For example, alkylating agents are now considered effective in the treatment of ovarian malignancies, but are not effective in all ovarian tumors and may even be completely ineffective. Some patients use multiple medications more than one course of treatment is still inevitable death. This is a gynecologic oncology physician urgently want to solve the problem.